The Golden Judokas are gunning for a fifth straight title, while the Lady Warriors hope to make it two in a row in the two-day event which will start at 1:30 p.m.
In the most recent competition last March 2020, UST nipped University of the Philippines to claim a four-peat in the men's side.
UE achieved a breakthrough on the women's side as it secured its first-ever crown, ending UST's five-year reign.
High school action, meanwhile, begins at 9 a.m.
UST annexed a fourth straight boys' crown, while UE kept the title for a third consecutive season in 2020.
"The technical meeting and draw were successfully done this afternoon and attended by the different coaches of these top universities," said UAAP Season 85 judo commissioner Dave Carter, who was joined by Philippine Judo Federation president and Ateneo coach Ali Sulit during the meeting.
"We wish everybody the best now that we are re-starting the face-to-face action! These are top athletes and everyone is excited."