The native of Silay City tallied 24 points, 14 rebounds, six steals, and two assists.
La Salle pulled away in the second quarter to lead the half, 32-17, and kept UP at bay from that point on, despite a close 20-17 scoring in the third quarter.
Pastrana and Bennette Revillosa used their size advantage late in the game as they scored eight and five points respectively in the last six minutes of the game.
Jona Lebico had 11 markers to lead UP in the scoring department.
Paul Ramos made his coaching debut for UP, replacing Kenneth Raval during the off-season. The Lady Maroons, however, dropped their 31st straight game.
DLSU 78 - Pastrana 24, Revillosa 13, Paraiso 8, Torres 7, Okoli 7, Sario 6, Quingco 5, Malarde 3, Del Campo 3, Binaohan 2, Dalsay 0, Jimenez 0, Jajurie 0, Espinas 0, Castillo 0, Camba 0, Arciga 0, El Hadad 0.
UP 47 - Lebico 11, Sanchez 9, Ordoveza 6, Gusilatar 6, Rivera 4, Pesquera 4, De Leon 3, Taulava 2, Gonzales 2, Domingo 0, Lucman 0, Larrosa 0, Hidalgo 0.
Quarterscores: 11-7, 32-17, 52-34, 78-47